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Image Search Results
Journal: Aging (Albany NY)
Article Title: Glucagon-like peptide-1 attenuated carboxymethyl lysine induced neuronal apoptosis via peroxisome proliferation activated receptor-γ
doi: 10.18632/aging.203351
Figure Lengend Snippet: PPAR-γ inhibition abolished the protective effect of GLP-1 on PC12 cells from apoptosis induced by CML. Results in ( A ) showed GW9662 abolished the protective effect of GLP-1 on PC12 cells from apoptosis induced by CML. ( B ) Showed the western blotting results of bcl2, bax, and GLP-1R. “a” in ( C ) showed the down-regulated bcl2 and GLP-1R as well as up-regulated bax levels between PC12 cells (treated by 50ug/ml CML and 100 nM GLP-1) with and without 5uM GW9662. Results in ( D ) showed the direct interactivity between PPAR-γ and GLP-1R promoter sequence. Data are represented as mean ± SD; n = 3 per group for results of western blotting.
Article Snippet: After CML stimulating, GLP-1 treatment and
Techniques: Inhibition, Western Blot, Sequencing